[Download] "Untranslated Gene Regions and Other Non-coding Elements" by Lucy W. Barrett, Sue Fletcher & Steve D. Wilton # Book PDF Kindle ePub Free
eBook details
- Title: Untranslated Gene Regions and Other Non-coding Elements
- Author : Lucy W. Barrett, Sue Fletcher & Steve D. Wilton
- Release Date : January 26, 2013
- Genre: Life Sciences,Books,Science & Nature,Professional & Technical,Medical,
- Pages : * pages
- Size : 679 KB
Description
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.